Actin, beta (ACTB) antibody

Details for Product No. ABIN153418
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Antigen
Synonyms
ACTA1, A, ACT5C, Ac5C, Act, Act-5C, Act5, Act5c, Actin, Actin/BAP47, Actin5C, BAP47, Bap47, CG4027, Dmel\\CG4027, M32055, T11, act, act 5C, act5C, actin, actin5C, anon-EST:fe2D2, beta-actin, beta-acti ... show more
ACTA1, A, ACT5C, Ac5C, Act, Act-5C, Act5, Act5c, Actin, Actin/BAP47, Actin5C, BAP47, Bap47, CG4027, Dmel\\CG4027, M32055, T11, act, act 5C, act5C, actin, actin5C, anon-EST:fe2D2, beta-actin, beta-actin/Bap47, cyt5C, l(1)G0009, l(1)G0010, l(1)G0025, l(1)G0079, l(1)G0117, l(1)G0177, l(1)G0245, l(1)G0330, l(1)G0420, l(1)G0486, BRWS1, PS1TP5BP1, Actx, E430023M04Rik, Bact, ACT-5, A26C1B, ACTB, POTE2alpha, POTEACTIN, actb, ps1tp5bp1, LOC563571, A26C1A, act-2, B-actin, LOC100136013, LOC100174883, LOC100304816 show less
Reactivity
Human, Mouse (Murine)
(322), (197), (182), (69), (54), (51), (40), (30), (29), (27), (23), (22), (11), (11), (9), (9), (7), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(207), (129), (18), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(12), (10), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Western Blotting (WB)
(314), (138), (88), (63), (60), (51), (27), (20), (19), (10), (9), (5), (4), (3), (2), (2), (1), (1)
Pubmed 3 references available
Catalog no. ABIN153418
Quantity 25 µL
Price
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Immunogen The epitope that this antibody recognizes maps to the N-terminus of human beta actinusing the numbering given in Swiss-prot entry P60709. The N-terminus of beta actin ishighly conserved with gamma actin. Initial tests show that this antibody recognizes bothbeta and gamma actin.
Specificity Detects a single clean band at 40kD representing actin. Species Reactivity: Human and Mouse.
Cross-Reactivity Human, Mouse (Murine)
Purification Affinity Purified
Alternative Name Actin beta / ACTB
Background In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have beenidentified. The alpha actins are found in muscle tissues and are a major constituent ofthe contractile apparatus. The beta and gamma actins coexist in most cell types ascomponents of the cyto-skeleton and as mediators of internal cell motility. Beta actinsare highly conserved proteins that are involved in cell motility, structure and integrity.Beta actins are cytoplasmic proteins ubiquitously expressed in all eukaryotic cells.Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in theform of a two-stranded helix. Each actin can bind to 4 others. This antibody serves as anexcellent loading control. Alternate Names: anti-ActG antibody, anti-ActG1 antibody, anti-Actin antibody, anti-Gamma1 antibody,anti-DFNA20 antibody, anti-A X actin like protein antibody, anti-Actx antibody, Anti-Betacytoskeletal actin antibody, Anti-Melanoma X actin antibody, anti-PS1TP5BP1 antibody.
Gene ID 60
Application Notes Suggested working dilutions: Western Blot 1:5,000-1:15,000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/ml
Buffer Tris-citrate/phosphate pH 7 to 8. Preservative: 0.09% Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
anti-Actin, beta (ACTB) antibody anti-Actin, beta (ACTB) antibody
General Watters, Kraja, Meucci et al.: "Genome-wide discovery of loci influencing chemotherapy cytotoxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 32, pp. 11809-14, 2004 (PubMed).

Sanue, Sinnett, Delvin et al.: "Localization and role of NPC1L1 in cholesterol absorption in human intestine." in: Journal of lipid research, Vol. 47, Issue 10, pp. 2112-20, 2006 (PubMed).

Kolokoltsov, Deniger, Fleming et al.: "Small interfering RNA profiling reveals key role of clathrin-mediated endocytosis and early endosome formation for infection by respiratory syncytial virus." in: Journal of virology, Vol. 81, Issue 14, pp. 7786-800, 2007 (PubMed).

Hosts (207), (129), (18), (2)
Reactivities (322), (197), (182), (69), (54), (51), (40), (30), (29), (27), (23), (22), (11), (11), (9), (9), (7), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (314), (138), (88), (63), (60), (51), (27), (20), (19), (10), (9), (5), (4), (3), (2), (2), (1), (1)
Conjugates (12), (10), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Epitopes (96), (29), (12), (9), (7), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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