Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) antibody

Details for Product No. ABIN153421
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Antigen
Synonyms CD169, SIGLEC-1, SN, dJ1009E24.1, Sn, Cd169, Siglec-1, SA, SIGLEC1, p210, pSn
Reactivity
Human
(65), (53), (39), (24), (17)
Host
Mouse
(44), (35), (21), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(17), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
(68), (38), (22), (20), (20), (18), (17), (9), (9), (4), (3), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN153421
Quantity 0.1 mg
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Immunogen Full-length purified human hSn(d1-4)Fc protein. [Swiss-prot# Q9BZZ2].
Clone HSn 7D2
Isotype IgG1
Specificity Species Reactivity: Reacts with Human. Not yet tested in other species. Localization: Isoform 1: Cell membrane, Single-pass type I membrane protein.Isoform 2: Secreted. Theoretical Molecular Weight: ~183 kDa.
Cross-Reactivity Human
Purification Purified
Alternative Name CD169 / SIGLEC1
Background The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily)that bind sialic acid and mediate cell-cell interactions. Family members includesialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesionmolecule that is expressed on activated macrophages in chronic inflammation and intumours. Alternate Names: anti-CD169 antibody, anti-Sialic Acid-binding Immunoglobulin-like Lectin 1 antibody,anti-Siglec 1 antibody.
Gene ID 6614
Application Notes Immunohistochemistry (paraffin-embedded, acetone-fixed, and frozen sections), FACS,RIA, ELISA*Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Concentration 1.1 mg/ml
Buffer PBS. Preservative: No presrvative.
Storage 4 °C
General Hartnell, Steel, Turley et al.: "Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations." in: Blood, Vol. 97, Issue 1, pp. 288-96, 2001 (PubMed).

Hosts (44), (35), (21), (3)
Reactivities (65), (53), (39), (24), (17)
Applications (68), (38), (22), (20), (20), (18), (17), (9), (9), (4), (3), (2), (1)
Conjugates (17), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (1), (1), (1), (1)
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