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Cyclin D1 (CCND1) antibody

Antigen

Cyclin D1 (CCND1)
Synonyms
BCL1, PRAD1, U21B31, D11S287E, cD1, Cyl-1, bcl-1, AI327039, DIP1, GCIP, Maid, SECC-8, SSEC-8, AU022347, cb161, cycd1, fb52e01, fc83a12, id:ibd1198, wu:fb52e01, wu:fc83a12, MGC109078, ccnd1b, MGC52909, ... show more
Clonality Monoclonal (SP4)
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
1 reference available
Catalog no. ABIN153471
Quantity 0.5 ml
Price Product not available in this region.
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anti-Cyclin D1 (CCND1) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name Cyclin D1
Gene ID 595, 12443, 58919
Immunogen Synthetic peptide from C-terminus of human cyclin D1.
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Format Supernatant
Isotype IgG
Clone SP4
Description Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions inassociation with cdk4 and / or cdk6 by phosphorylating the Rb protein. It is a putativeproto-oncogene overexpressed in a wide variety of human neoplasmsincluding mantle cell lymphomas (MCL). Alternate Names: Anti-B cell ccl/lymphoma 1 antibody, Anti-B cell leukemia 1 antibody, Anti-BCL1antibody, Anti-BCL1 oncogene antibody, Anti-CCND 1 antibody, Anti-CCND1 antibody,Anti-CCND1 protein antibody, Anti-CCND1/IGHG1 fusion gene antibody,Anti-D11S287E antibody, Anti-G1/S specific cyclin D1 antibody, Anti-Parathyroidadenomatosis 1 antibody, Anti-PRAD1 antibody, Anti-PRAD1 oncogene antibody,Anti-U21B31 antibody.
Specificity Species Reactivity: Cross-reacts with Mouse, Rat and Human. Not yet tested in other species. Localization: Nuclear.
Synonyms BCL1, PRAD1, U21B31, D11S287E, cD1, Cyl-1, bcl-1, AI327039, DIP1, GCIP, Maid, SECC-8, SSEC-8, AU022347, cb161, cycd1, fb52e01, fc83a12, id:ibd1198, wu:fb52e01, wu:fc83a12, MGC109078, ccnd1b, MGC52909, MGC132138, ccnd1, MGC53090, bcl1, prad1, u21b31, MGC69515, d11s287e, CCND1, ccndbp1, MGC137744, ZHM, CCNDBP1, MGC133757, DKFZp468E2216, DKFZp469C1216, DKFZp469H0317

Application Details
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Application Notes Suggested working dilutions: immunohistochemistry 1:100,Positive Controls: Breast carcinomas or mantle cell lymphoma
Purification Supernatant
Buffer Preservative: 15mM Sodium Azide.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.Notes:
Research Area Cancer, Cell Cycle
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Cheuk, Wong, Wong et al.: "Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody." in: The American journal of surgical pathology, Vol. 28, Issue 6, pp. 801-7, 2004 (PubMed).