PTCRA antibody (C-Term)

Catalog No. ABIN1536828

Product Details anti-PTCRA Antibody

Target: PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))

Binding Specificity: AA 197-225, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTCRA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTCRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human PTCRA.

Clone: RB39212

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PTCRA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PTCRA

Target: PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))

Alternative Name: PTCRA (PTCRA Products)

Synonyms: gp33 antibody, pT-alpha antibody, pT-alpha-TCR antibody, pT[a] antibody, pTa antibody, pTalpha antibody, PT-ALPHA antibody, PTA antibody, pre T cell antigen receptor alpha antibody, pre T-cell antigen receptor alpha antibody, Ptcra antibody, PTCRA antibody

Background: In immature T cells the T-cell receptor beta-chain gene (TCRB, MIM 186930) is rearranged and expressed before the TCRA (MIM 186880) chain. At this early stage, TCRB can associate with the pre-T-cell receptor alpha chain (PTCRA). The PTCRA, together with TCRB and the CD3 complex (see MIM 186740), minimally make up the pre-T cell receptor (pre-TCR), which regulates early T cell development.

Molecular Weight: 29266

Gene ID: 171558

NCBI Accession: NP_001230097, NP_001230098, NP_001230099, NP_612153

UniProt: Q6ISU1

Pathways: Cancer Immune Checkpoints