KHDRBS1 antibody (C-Term)

Catalog No. ABIN1537301

Product Details anti-KHDRBS1 Antibody

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Binding Specificity: AA 414-443, C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHDRBS1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: C, H, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1.

Clone: RB40286

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Mouse Khdrbs1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-KHDRBS1 antibody (ABIN1537301)

Zhang, Yu, Li, Jiang, Zhou: "Utility of SAM68 in the progression and prognosis for bladder cancer." in: BMC cancer, Vol. 15, pp. 364, (2015) (PubMed).

Target Details for KHDRBS1

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Alternative Name: Khdrbs1 (KHDRBS1 Products)

Synonyms: Sam68 antibody, p62 antibody, p68 antibody, fj90g10 antibody, khdrbs1 antibody, wu:fa18g12 antibody, wu:fa56c01 antibody, wu:fc91b01 antibody, wu:fj90g10 antibody, zgc:113899 antibody, KHDRBS1 antibody, P62 antibody, khdrbs1l antibody, sb:cb97 antibody, wu:fb07d11 antibody, wu:fi43c05 antibody, zgc:85948 antibody, KH RNA binding domain containing, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1a antibody, KH domain containing, RNA binding, signal transduction associated 1 antibody, KH domain containing, RNA binding, signal transduction associated 1 S homeolog antibody, KH domain containing, RNA binding, signal transduction associated 1b antibody, KHDRBS1 antibody, khdrbs1a antibody, khdrbs1 antibody, Khdrbs1 antibody, khdrbs1.S antibody, khdrbs1b antibody

Background: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

Molecular Weight: 48371

Gene ID: 20218

NCBI Accession: NP_035447

UniProt: Q60749

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy