PPFIBP1 antibody (AA 588-617)

Catalog No. ABIN1538519

Product Details anti-PPFIBP1 Antibody

Target: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Binding Specificity: AA 588-617

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPFIBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1.

Clone: RB37193

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PPFIBP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PPFIBP1

Target: PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))

Alternative Name: PPFIBP1 (PPFIBP1 Products)

Synonyms: liprin-beta-1 antibody, L2 antibody, SGT2 antibody, hSGT2 antibody, hSgt2p antibody, 4632409B19Rik antibody, AW214454 antibody, AW261454 antibody, PPFIA binding protein 1 antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antibody, Ppfibp1 antibody, ppfibp1 antibody, ppfibp1.S antibody, PPFIBP1 antibody

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molecular Weight: 114024

Gene ID: 8496

NCBI Accession: NP_001185844, NP_001185845, NP_003613, NP_803193

UniProt: Q86W92