MTIF2 antibody (N-Term)

Catalog No. ABIN1539049

Product Details anti-MTIF2 Antibody

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Binding Specificity: AA 138-167, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTIF2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MTIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human MTIF2.

Clone: RB36592

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MTIF2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MTIF2

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Alternative Name: MTIF2 (MTIF2 Products)

Background: During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38 % amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Molecular Weight: 81317

Gene ID: 4528

NCBI Accession: NP_001005369, NP_002444

UniProt: P46199

Pathways: Ribonucleoprotein Complex Subunit Organization