TRPC4AP antibody (N-Term)

Catalog No. ABIN1539407

Product Details anti-TRPC4AP Antibody

Target: TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))

Binding Specificity: AA 49-75, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC4AP antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRPC4AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-75 amino acids from the N-terminal region of human TRPC4AP.

Clone: RB38628

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TRPC4AP Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for TRPC4AP

Target: TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))

Alternative Name: TRPC4AP (TRPC4AP Products)

Synonyms: TRPC4AP antibody, MGC130977 antibody, 4833429F06Rik antibody, D2Ertd113e antibody, Trrp4ap antibody, mFLJ00177 antibody, truss antibody, C20orf188 antibody, TRRP4AP antibody, TRUSS antibody, transient receptor potential cation channel subfamily C member 4 associated protein antibody, transient receptor potential cation channel, subfamily C, member 4 associated protein L homeolog antibody, transient receptor potential cation channel, subfamily C, member 4 associated protein antibody, TRPC4AP antibody, trpc4ap.L antibody, trpc4ap antibody, Trpc4ap antibody

Background: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Molecular Weight: 90852

Gene ID: 26133

NCBI Accession: NP_056453, NP_955400

UniProt: Q8TEL6