This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GABRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human GABRE.
GABRE antibody, gamma-aminobutyric acid type A receptor epsilon subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit epsilon antibody, GABRE antibody, Gabre antibody
Background
The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.