Nuclease-Sensitive Element-Binding Protein 1 (YBX1) (N-Term) antibody

Antigen: Nuclease-Sensitive Element-Binding Protein 1 (YBX1)

Synonyms: YB1, BP-8, CSDB, DBPB, YB-1, CSDA2, NSEP1, NSEP-1, MDR-NF1, MGC104858, MGC110976, MGC117250

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN155059

Additional Information

Alternative name: YB-1 (N-Term)

Gene ID: 4904

Isotype: IgG  (Matching secondary antibodies)

Description: Members of Y-box binding protein family all contain a DNA binding domain, called the cold shock domain, comprising of 80 amino acids, which is highly conserved from prokaryotes to eukaryotes. Y-box binding protein-1 (YB-1) is a prototypic member of this f

Application Details

Application Notes: WB: 1:1000. IHC (p): 1:50 to 1:200 depending on type of tissue

Concentration: 2 mg/ml

Purification: Affinitiy-purified

Storage: Store aliquots at -20 C. Avoid repeated thawing and freezing

Research Area: Cancer

Restrictions: For Research Use only

Images

Western Blot

IHC

Publications

Publications: Krohn R, Raffetseder U, Bot I et al.: "Y-Box Binding Protein-1 Controls CC Chemokine Ligand-5 (CCL5) Expression in Smooth Muscle Cells and Contributes to Neointima Formation in Atherosclerosis-Prone Mice" in: Circulation, Vol. Epub ahead of print, 2007 (PubMed).

Frye, Halfter, Djudjaj et al.: "Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen." in: EMBO reports, Vol. 10, Issue 7, pp. 783-9, 2009 (PubMed).

Rauen, Raffetseder, Frye et al.: "YB-1 acts as ligand for Notch-3 receptors and modulates receptor activation." in: The Journal of biological chemistry, 2009 (PubMed).