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TEK antibody (Extracellular Domain) (Biotin)

TEK Reactivity: Human WB, FACS, EIA Host: Mouse Monoclonal Cl-9 Biotin
Catalog No. ABIN155164
  • Target See all TEK Antibodies
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Binding Specificity
    • 19
    • 19
    • 16
    • 11
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivity
    • 136
    • 66
    • 49
    • 22
    • 4
    • 3
    Human
    Host
    • 128
    • 17
    • 3
    • 2
    • 2
    Mouse
    Clonality
    • 134
    • 18
    Monoclonal
    Conjugate
    • 70
    • 10
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEK antibody is conjugated to Biotin
    Application
    • 80
    • 59
    • 40
    • 40
    • 36
    • 27
    • 14
    • 13
    • 12
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificity
    The unconjugated antibody will detect native TIE-2/tek.
    Purification
    Protein G chromatography
    Immunogen
    Recombinant human soluble extracellular TIE-2
    Clone
    Cl-9
    Isotype
    IgG1
    Top Product
    Discover our top product TEK Primary Antibody
  • Application Notes
    ELISA. Western Blot. FACS analysis and cell sorting: 2-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Reconstitute to a concentration of 50 μg/mL with sterile PBS solution containing 0.1 % BSA
    Buffer
    0.1 M Tris-Cl, 0.1 M NaCl, 0.02 % NaN3, pH 7.4 containing 50x BSA as stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    This product is photosensitive and should be protected from light
    Storage
    4 °C
    Storage Comment
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Alternative Name
    CD202b / TEK (TEK Products)
    Synonyms
    TEK antibody, DKFZp469E064 antibody, AA517024 antibody, Cd202b antibody, Hyk antibody, Tie2 antibody, tie-2 antibody, CD202B antibody, TIE-2 antibody, TIE2 antibody, VMCM antibody, VMCM1 antibody, Tie-2 antibody, tie2 antibody, TEK receptor tyrosine kinase antibody, angiopoietin-1 receptor antibody, TEK tyrosine kinase, endothelial antibody, TEK antibody, LOC100408334 antibody, tek antibody, Tek antibody
    Background
    TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
    Gene ID
    7010
    NCBI Accession
    NP_000450
    UniProt
    Q02763
    Pathways
    RTK Signaling, Growth Factor Binding
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