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Cytochrome C antibody (N-Term)

CYCS Reactivity: Human, Rat, Mouse WB, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1574153
  • Target See all Cytochrome C (CYCS) Antibodies
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Binding Specificity
    • 16
    • 13
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 140
    • 111
    • 91
    • 45
    • 32
    • 24
    • 22
    • 19
    • 18
    • 16
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 84
    • 70
    • 7
    • 1
    Rabbit
    Clonality
    • 83
    • 78
    • 1
    Polyclonal
    Conjugate
    • 101
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cytochrome C antibody is un-conjugated
    Application
    • 132
    • 47
    • 41
    • 39
    • 35
    • 33
    • 27
    • 23
    • 14
    • 14
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Specificity
    Rabbit Anti-Cytochrome C Polyclonal Antibody detects endogenous levels of human and mouse Cytochrome C. Predicted to react with rat Cytochrome C according to sequence homology.
    Cross-Reactivity (Details)
    Rabbit Anti-Cytochrome C Polyclonal Antibody detects endogenous levels of human and mouse Cytochrome C. Predicted to react with rat Cytochrome C according to sequence homology.
    Purification
    Immunoaffinity chromatography.
    Immunogen
    KLH-coupled synthetic peptide from N-terminal of human Cytochrome C .
    Isotype
    IgG
    Top Product
    Discover our top product CYCS Primary Antibody
  • Application Notes
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    Western blot: 1-2 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cells
    Other applications: user-optimized
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4, containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C/-20 °C
    Storage Comment
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • Li, Yu, Gui, Xie, Hong, Zhao, Sheng, Sang, Sun, Wang, Shen, Hong: "Titanium dioxide nanoparticles relieve silk gland damage and increase cocooning of Bombyx mori under phoxim-induced toxicity." in: Journal of agricultural and food chemistry, Vol. 61, Issue 50, pp. 12238-43, (2013) (PubMed).

  • Target
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Alternative Name
    Cytochrome C (CYCS Products)
    Synonyms
    CYC antibody, HCS antibody, THC4 antibody, cyct antibody, cyc antibody, hcs antibody, CYCS antibody, cytc antibody, CYCSA antibody, CG17903 antibody, Cyt C antibody, Cyt c antibody, Cyt-c2 antibody, CytC-2 antibody, Cytc antibody, Cytc-p antibody, DC4 antibody, DMc01 antibody, Dmel\\CG17903 antibody, cyt c antibody, cyt c-p antibody, cyt-c-p antibody, cyt-c2 antibody, cyt.c antibody, cytochrome c antibody, dc4 antibody, pDMc01 antibody, wu:fk52b01 antibody, zgc:86706 antibody, ENSMUSG00000058927 antibody, cytochrome c, somatic antibody, cytochrome c, somatic S homeolog antibody, Cytochrome c proximal antibody, cytochrome c, somatic b antibody, cytochrome c, somatic pseudogene antibody, cytochrome c-like antibody, cytochrome c antibody, CYCS antibody, cycs.S antibody, cycs antibody, Cycs antibody, Cyt-c-p antibody, cycsb antibody, Gm10053 antibody, LOC100724240 antibody, CYC antibody, LOC100847700 antibody, LOC101107954 antibody, LOC106829744 antibody, LOC106992390 antibody, LOC102085712 antibody
    Background
    Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.Rabbit Anti-Cytochrome C Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human Cytochrome C (Swiss Prot: P99999).
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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