IFNAR1 antibody (Interferon (Alpha, beta and Omega) Receptor 1) (pSer535)

Details for Product anti-IFNAR1 Antibody No. ABIN1582221, Supplier: Log in to see
Antigen
  • ifnar1
  • IFNAR1
  • CD118
  • Ifar
  • Ifnar
  • Ifrc
  • Infar
  • AVP
  • IFN-alpha-REC
  • IFNAR
  • IFNBR
  • IFRC
  • IFN-R-1
  • interferon (alpha, beta and omega) receptor 1
  • interferon-alpha/beta receptor alpha chain-like
  • interferon receptor 1
  • interferon (alpha and beta) receptor 1
  • type I interferon receptor 1e
  • IFNAR1
  • ifnar1
  • LOC100230358
  • Ifnar1
  • IFNAR1E
Alternatives
anti-Human IFNAR1 antibody for Flow Cytometry
Epitope
pSer535, pSer539
26
26
17
17
15
15
10
10
8
7
6
6
5
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Sheep (Ovine), Rat (Rattus)
175
45
26
3
2
1
1
1
Host
Rabbit
119
58
28
Clonality
Polyclonal
Conjugate
This IFNAR1 antibody is un-conjugated
14
11
11
9
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
115
72
66
38
26
16
9
7
6
5
5
4
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding pSer535,pSer539 of human interferon-a receptor, type I, subunit I.
Cross-Reactivity Cow (Bovine), Dog (Canine), Mouse (Murine), Sheep (Ovine), Rat (Rattus)
Purification Antibody was purified by immunogen affinity chromatography.
Alternative Name IFNAR1 (IFNAR1 Antibody Abstract)
Background Interferon-a Receptor, Type I, Subunit I (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. This interferon receptor is a receceptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Down regulation of IFNAR1 is influenced by phosphorylation of Serine 535 and 539.
UniProt P17181
Research Area Chromatin and Nuclear Signaling, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling, Hepatitis C
Application Notes ELISA: 1:1.000, WB: 1:1.000, IHC: 1:1.000
Restrictions For Research Use only
Format Liquid
Buffer Each vial contains 0.1 mL IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol.
Handling Advice Minimize freeze-thaw cycles.
Storage -20°C
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) (pSer535), (pSer539) antibody (ABIN1582221) anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) (pSer535), (pSer539) antibody
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