CRTC3 antibody (AA 151-260) (Alexa Fluor 350)

Catalog No. ABIN1693582

Product Details anti-CRTC3 Antibody (Alexa Fluor 350)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Binding Specificity: AA 151-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTC3/TORC3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3/TORC3 (CRTC3 Products)

Synonyms: torc3 antibody, MGC146372 antibody, 2610312F20Rik antibody, 6332415K15Rik antibody, AI429792 antibody, BC011210 antibody, TORC3 antibody, RGD1309666 antibody, TORC-3 antibody, CREB regulated transcription coactivator 3 antibody, CREB regulated transcription coactivator 3 L homeolog antibody, CRTC3 antibody, crtc3 antibody, Crtc3 antibody, crtc3.L antibody

Background:

Synonyms: CREB regulated transcription coactivator 3, CREB-regulated transcription coactivator 3, CRTC 3, CRTC3, CRTC3_HUMAN, FLJ21868, TORC 3, TORC-3, TORC3, Transducer of CREB protein 3, Transducer of regulated cAMP response element binding protein CREB 3, Transducer of regulated cAMP response element binding protein 3, Transducer of regulated cAMP response element-binding protein 3, Transducer of regulated CREB protein 3.

Background: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.

Gene ID: 64784

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection