IDUA antibody (AA 101-200) (Alexa Fluor 488)

Catalog No. ABIN1694892

Product Details anti-IDUA Antibody (Alexa Fluor 488)

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Binding Specificity: AA 101-200

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDUA antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IDUA

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IDUA

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Alternative Name: Idua (IDUA Products)

Synonyms: IDA antibody, MPS1 antibody, 6030426D08 antibody, alpha-L-iduronidase antibody, MGC80842 antibody, si:ch211-12e13.9 antibody, IDUA antibody, iduronidase, alpha-L- antibody, iduronidase, alpha-L- L homeolog antibody, alpha-L-iduronidase antibody, IDUA antibody, Idua antibody, idua.L antibody, idua antibody, LOC5564727 antibody

Background:

Synonyms: IDA, MPS1, Alpha-L-iduronidase, IDUA

Background: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008].

Gene ID: 3425

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process