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GMPPB antibody (AA 111-210) (Alexa Fluor 488)

GMPPB Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1696081
  • Target See all GMPPB Antibodies
    GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))
    Binding Specificity
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 111-210
    Reactivity
    • 39
    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 3
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GMPPB antibody is conjugated to Alexa Fluor 488
    Application
    • 27
    • 12
    • 12
    • 12
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GMPPB
    Isotype
    IgG
    Top Product
    Discover our top product GMPPB Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))
    Alternative Name
    GMPPB (GMPPB Products)
    Synonyms
    MDDGA14 antibody, MDDGB14 antibody, MDDGC14 antibody, AI317178 antibody, E430010H19 antibody, RGD1560458 antibody, gmppl antibody, zgc:92026 antibody, GMPPB antibody, gmppb antibody, gmppb-a antibody, gmppb-b antibody, GDP-mannose pyrophosphorylase B antibody, GDP-mannose pyrophosphorylase B L homeolog antibody, GDP-mannose pyrophosphorylase B S homeolog antibody, GMPPB antibody, Gmppb antibody, gmppb antibody, LOAG_13550 antibody, gmppb.L antibody, gmppb.S antibody
    Background

    Synonyms: GDP mannose pyrophosphorylase B, GDP-mannose pyrophosphorylase B, GMPPB, GMPPB_HUMAN, GTP-mannose-1-phosphate guanylyltransferase beta, KIAA1851, Mannose 1 phosphate guanylyltransferase, Mannose-1-phosphate guanyltransferase beta.

    Background: GMPPB is a 360 amino acid protein that belongs to the transferase hexapeptide repeat family and is involved in protein modification pathways. Functioning as a GDP-mannose pyrophosphorylase, GMPPB enzymatically catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose and a free phosphate, a reaction that is involved in the production of N-linked oligosaccharides. Defects in the gene encoding GMPPB that cause errors in the glycosylation pathway may lead to congenital disorders of glycosylation (CDG). CDGs are multisystemic diseases that often involve both the central and peripheral nervous systems and are often characterized by endocrine and coagulation disorders. GMPPB is expressed as two isoforms due to alternative splicing events.

    Gene ID
    29925
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