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GEMIN6 antibody (AA 21-120) (Alexa Fluor 647)

GEMIN6 Reactivity: Human, Rat WB, IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1698498
  • Target See all GEMIN6 Antibodies
    GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
    Binding Specificity
    • 14
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivity
    • 30
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 26
    • 4
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GEMIN6 antibody is conjugated to Alexa Fluor 647
    Application
    • 25
    • 12
    • 12
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Gemin 6
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN6 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
    Alternative Name
    Gemin 6 (GEMIN6 Products)
    Synonyms
    2610019B15Rik antibody, 2810470M17Rik antibody, gemin6 antibody, gem nuclear organelle associated protein 6 antibody, gem (nuclear organelle) associated protein 6 antibody, gem nuclear organelle associated protein 6 S homeolog antibody, GEMIN6 antibody, Gemin6 antibody, gemin6.S antibody
    Background

    Synonyms: FLJ23459, Gemin6, Gemin-6, Gem nuclear organelle associated protein 6, Gem-associated protein 6, GEMI6, GEMI6_HUMAN, Gemin-6, GEMIN6, SIP2.

    Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).

    Gene ID
    79833
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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