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EPRS antibody (AA 651-750) (Alexa Fluor 647)

EPRS Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1698875
  • Target See all EPRS Antibodies
    EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))
    Binding Specificity
    • 14
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 651-750
    Reactivity
    • 49
    • 35
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 50
    Rabbit
    Clonality
    • 50
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPRS antibody is conjugated to Alexa Fluor 647
    Application
    • 30
    • 12
    • 12
    • 9
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glutamyl Prolyl tRNA syntase/ProRS
    Isotype
    IgG
    Top Product
    Discover our top product EPRS Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))
    Alternative Name
    Glutamyl Prolyl tRNA synthetase/ProRS (EPRS Products)
    Synonyms
    EARS antibody, GLUPRORS antibody, PARS antibody, QARS antibody, QPRS antibody, wu:fb38d08 antibody, wu:ft34d10 antibody, 2410081F06Rik antibody, 3010002K18Rik antibody, C79379 antibody, Qprs antibody, glutamyl-prolyl-tRNA synthetase antibody, glutamyl-prolyl-tRNA synthetase S homeolog antibody, EPRS antibody, eprs antibody, eprs.S antibody, Eprs antibody
    Background

    Synonyms: EARS, PARS, QARS, QPRS, PIG32, GLUPRORS, Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase, Cell proliferation-inducing gene 32 protein, Glutamatyl-prolyl-tRNA synthetase, EPRS, GLNS

    Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

    Gene ID
    2058
    UniProt
    P07814
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