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TXNDC12 antibody (AA 21-120) (Alexa Fluor 647)

TXNDC12 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1698991
  • Target See all TXNDC12 Antibodies
    TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    AA 21-120
    Reactivity
    • 47
    • 18
    • 9
    Human
    Host
    • 47
    Rabbit
    Clonality
    • 46
    • 1
    Polyclonal
    Conjugate
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNDC12 antibody is conjugated to Alexa Fluor 647
    Application
    • 33
    • 22
    • 18
    • 12
    • 12
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ERp19
    Isotype
    IgG
    Top Product
    Discover our top product TXNDC12 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))
    Alternative Name
    ERp19 (TXNDC12 Products)
    Synonyms
    AG1 antibody, AGR1 antibody, ERP16 antibody, ERP18 antibody, ERP19 antibody, PDIA16 antibody, TLP19 antibody, hAG-1 antibody, hTLP19 antibody, 0610040B21Rik antibody, ERp16 antibody, ERp19 antibody, RGD1305960 antibody, thioredoxin domain containing 12 antibody, thioredoxin domain containing 12 (endoplasmic reticulum) antibody, TXNDC12 antibody, Txndc12 antibody
    Background

    Synonyms: AG1, AGR1, anterior gradient homolog 1, endoplasmic reticulum protein ERp19, endoplasmic reticulum resident protein 18, endoplasmic reticulum resident protein 19, endoplasmic reticulum thioredoxin superfamily member, 18 kDa, ER protein 18, ER protein 19, ERP 18, ERP16, ERP19, hAG 1, hAG1, hTLP19, PDIA16, protein disulfide isomerase family A, member 16, thioredoxin domain containing 12 endoplasmic reticulum, Thioredoxin domain-containing protein 12, thioredoxin like protein p19, TLP19, TXNDC12, TXD12_HUMAN.

    Background: Endoplasmic reticulum proteins (ERps) are widely expressed proteins and localize to the ER. ERp19, ERp29, ERp46, ERp57 and ERp72 may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases, phospholipases or a combination of these. ERp19, also designated thioredoxin domain-containing protein 12 (TXNDC12), and ERp46, also designated thioredoxin domain containing 5 (TXNDC5), belong to the thioredoxin superfamily and contain a thioredoxin fold with a consensus active-site sequence (CxxC). Both ERp19 and ERp46 are widely expressed ER luminal proteins that are most abundant in the liver and are enriched in purified liver ER vesicles. ERp19 shows significant protein thiol-disulfide oxidase activity in vitro, which is dependent on the presence of both active-site cysteines.

    Gene ID
    51060
    Pathways
    Cell RedoxHomeostasis
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