Gasdermin Like (AA 171-270) antibody (Biotin)
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- Target
- Gasdermin Like
- Binding Specificity
- AA 171-270
- Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Biotin
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GSDML/Gasdermin like
- Isotype
- IgG
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-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- Gasdermin Like
- Background
-
Synonyms: 123, 156, Gasdermin B, Gasdermin like protein, Gasdermin-B, Gasdermin-like protein, GSDMB, GSDMB_HUMAN, GSDML, PP4052, PRO2521.
Background: GSDML is a member of the GSDMDC (gasdermin-domain containing) family of proteins. Members of the GSDMDC family are involved in a wide variety of cellular processes, including cell-cycle control, extracellular matrix production, differentiation and apoptosis, and have been associated with the development and progression of cancer. GSDML is a widely expressed protein found in both cancerous and non-cancerous tissues localizing to the cytoplasm and in secretory vesicles. The gene encoding GSDML is thought to have been generated by a duplication event of the GSDM1 gene which encodes gasdermin. In addition, various isoforms exist for GSDML.
- Gene ID
- 55876
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