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CTBS antibody (AA 1-100) (Biotin)

CTBS Reactivity: Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700252
  • Target See all CTBS Antibodies
    CTBS (Chitobiase, Di-N-Acetyl (CTBS))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 17
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 23
    • 3
    • 1
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTBS antibody is conjugated to Biotin
    Application
    • 27
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CTBS
    Isotype
    IgG
    Top Product
    Discover our top product CTBS Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    CTBS (Chitobiase, Di-N-Acetyl (CTBS))
    Alternative Name
    CTBS (CTBS Products)
    Synonyms
    CTB antibody, 2210401K11Rik antibody, chitobiase antibody, chitobiase, di-N-acetyl- antibody, CTBS antibody, Ctbs antibody
    Background

    Synonyms: Chitobiase di N acetyl, CTB, Di N acetylchitobiase, OTTHUMP00000011570, DIAC_HUMAN.

    Background: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

    Gene ID
    1486
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