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FXYD6 antibody (AA 15-75) (Biotin)

FXYD6 Reactivity: Human WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700291
  • Target See all FXYD6 Antibodies
    FXYD6 (FXYD Domain Containing Ion Transport Regulator 6 (FXYD6))
    Binding Specificity
    • 14
    • 5
    • 2
    • 1
    • 1
    AA 15-75
    Reactivity
    • 37
    • 15
    • 15
    Human
    Host
    • 37
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FXYD6 antibody is conjugated to Biotin
    Application
    • 24
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FXYD6
    Isotype
    IgG
    Top Product
    Discover our top product FXYD6 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    FXYD6 (FXYD Domain Containing Ion Transport Regulator 6 (FXYD6))
    Alternative Name
    FXYD6 (FXYD6 Products)
    Synonyms
    0610030I18Rik antibody, Php antibody, FXYD domain containing ion transport regulator 6 antibody, FXYD domain-containing ion transport regulator 6 antibody, FXYD6 antibody, Fxyd6 antibody
    Background

    Synonyms: FXYD domain containing ion transport regulator 6, FXYD domain containing ion transport regulator 6 precursor, Phosphohippolin, UNQ521/PRO1056, FXYD6_HUMAN.

    Background: The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids. Members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, mammary tumor protein), FXYD4 (CHIF) and FXYD5 (RIC). FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.

    Gene ID
    53826
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