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HGD antibody (AA 351-445) (FITC)

HGD Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN1709235
  • Target See all HGD Antibodies
    HGD (Homogentisate 1,2-Dioxygenase (HGD))
    Binding Specificity
    • 14
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-445
    Reactivity
    • 31
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 41
    • 5
    Rabbit
    Clonality
    • 43
    • 3
    Polyclonal
    Conjugate
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HGD antibody is conjugated to FITC
    Application
    • 35
    • 14
    • 12
    • 12
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HGD
    Isotype
    IgG
    Top Product
    Discover our top product HGD Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HGD (Homogentisate 1,2-Dioxygenase (HGD))
    Alternative Name
    Hgd (HGD Products)
    Synonyms
    CG4779 antibody, Dmel\\CG4779 antibody, PSPTO3551 antibody, DDBDRAFT_0185702 antibody, DDBDRAFT_0191461 antibody, DDB_0185702 antibody, DDB_0191461 antibody, Hgo antibody, aku antibody, hgo antibody, AKU antibody, HGO antibody, homogentisate 1,2-dioxygenase antibody, Homogentisate 1,2-dioxygenase antibody, homogentisate 1, 2-dioxygenase antibody, homogentisate 1,2-dioxygenase L homeolog antibody, hgo antibody, HGD antibody, hmgA antibody, Shewana3_2481 antibody, hgd antibody, BC1002_0545 antibody, BC1003_0502 antibody, BC1001_0489 antibody, Sinme_2995 antibody, Sphch_0441 antibody, Hgd antibody, hgd.L antibody
    Background

    Synonyms: 2-dioxygenase, AKU, FLJ94126, hgd, HGD_HUMAN, HGO, Homogentisate 1 2 dioxygenase, Homogentisate 1, Homogentisate oxidase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.

    Background: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

    Gene ID
    3081
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