GBA2 antibody (AA 601-700) (HRP)

Catalog No. ABIN1711697

Product Details anti-GBA2 Antibody (HRP)

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Binding Specificity: AA 601-700

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBA2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GBA2

Target: GBA2 (Glucosidase, beta (Bile Acid) 2 (GBA2))

Alternative Name: GBA2 (GBA2 Products)

Synonyms: TLN1 antibody, F630034E04 antibody, SPG46 antibody, talin 1 antibody, glucosidase, beta (bile acid) 2 antibody, glucosylceramidase beta 2 antibody, glucosidase beta 2 antibody, TLN1 antibody, gba2 antibody, GBA2 antibody, Gba2 antibody

Background:

Synonyms: AD035, SPG46, NLGase, Non-lysosomal glucosylceramidase, Beta-glucocerebrosidase 2, Beta-glucosidase 2, Glucosylceramidase 2, GBA2, KIAA1605

Background: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

Gene ID: 57704

UniProt: Q9HCG7