ACAA1 antibody (AA 231-330) (HRP)

Catalog No. ABIN1712103

Product Details anti-ACAA1 Antibody (HRP)

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Binding Specificity: AA 231-330

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABLIM3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ACAA1

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Alternative Name: ACAA1 (ACAA1 Products)

Synonyms: ACAA antibody, PTHIO antibody, THIO antibody, Acaa antibody, Acaa1 antibody, D9Ertd25e antibody, PTL antibody, zgc:92385 antibody, acaa antibody, pthio antibody, thio antibody, A2MP antibody, Pktaa antibody, acetyl-CoA acyltransferase 1 antibody, acetyl-Coenzyme A acyltransferase 1A antibody, acetyl-CoA acyltransferase 1 L homeolog antibody, ACP synthase antibody, alpha-2-macroglobulin pseudogene 1 antibody, acetyl-CoA acyltransferase 1A antibody, ACAA1 antibody, Acaa1a antibody, acaa1.L antibody, acaa1 antibody, AF_RS00150 antibody, A2MP1 antibody, Acaa1 antibody

Background:

Synonyms: 3 ketoacyl CoA thiolase peroxisomal, 3-ketoacyl-CoA thiolase, ACAA, ACAA1, Acetyl CoA acyltransferase 1, Acetyl Coenzyme A acyltransferase 1, Acetyl-CoA acyltransferase, Acetyl-Coenzyme A acyltransferase 1 peroxisomal 3 oxoacyl Coenzyme A, Beta ketothiolase, Beta-ketothiolase, Peroxisomal 3 oxoacyl CoA thiolase, Peroxisomal 3 oxoacyl Coenzyme A thiolase, Peroxisomal 3-oxoacyl-CoA thiolase, peroxisomal, PTHIO, THIK_HUMAN, THIO.

Background: ACAA1 is a 424 amino acid member of the thiolase family of enzymes and is involved in lipid metabolism. Localized to the peroxisome, ACAA1 catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. ACAA1 shows high enzymatic activity in liver, kidney, intestine and white adipose tissue in rats, where it exists as two types, namely type A and type B. Human ACAA1 shares 86 % amino acid identity with its rat counterpart, suggesting a conserved function for ACAA1 among different species.

Gene ID: 30

Pathways: Monocarboxylic Acid Catabolic Process