DAAM2 antibody (AA 161-260) (HRP)

Catalog No. ABIN1712237

Product Details anti-DAAM2 Antibody (HRP)

Target: DAAM2 (Dishevelled Associated Activator of Morphogenesis 2 (DAAM2))

Binding Specificity: AA 161-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAAM2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAAM2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DAAM2

Target: DAAM2 (Dishevelled Associated Activator of Morphogenesis 2 (DAAM2))

Alternative Name: DAAM2 (DAAM2 Products)

Synonyms: dJ90A20A.1 antibody, 2310016D11Rik antibody, AI843643 antibody, AW557870 antibody, DAAM2 antibody, dishevelled associated activator of morphogenesis 2 antibody, DAAM2 antibody, Daam2 antibody, daam2 antibody

Background:

Synonyms: DAAM2, DAAM2_HUMAN, Disheveled-associated activator of morphogenesis 2, dishevelled associated activator of morphogenesis 2, dJ90A20A.1, KIAA0381, MGC90515, RP1 278E11.1.

Background: DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Gene ID: 23500