DAPK2 antibody (pSer318) (HRP)

Catalog No. ABIN1712439

Product Details anti-DAPK2 Antibody (HRP)

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Binding Specificity: pSer318

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAPK2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human DAP Kinase 2 around the phosphorylation site of Ser318

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DAPK2

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Alternative Name: DAP Kinase 2 (DAPK2 Products)

Synonyms: drp1 antibody, drp-1 antibody, DAPK2 antibody, dapk2 antibody, DRP-1 antibody, DRP1 antibody, death-associated protein kinase 2 L homeolog antibody, death associated protein kinase 2 antibody, death-associated protein kinase 2b antibody, death-associated protein kinase 2 antibody, dapk2.L antibody, DAPK2 antibody, dapk2b antibody, dapk2 antibody, Dapk2 antibody

Background:

Synonyms: DAP Kinase 2 phospho S318, p-DAP Kinase 2 phospho S318, Death associated protein kinase 2, DAK 2, DAK2, DAP kinase related protein 1, DAPK 2, DAPK2, Death associated protein kinase 2, DRP 1, DRP1, DRP-1, MGC119312, DAP kinase 2, DAP kinase related protein 1, DAP kinase related protein 1 beta isoform, DAP-kinase-related protein 1, DAPK 2, DAPK2, DAPK2_HUMAN, Death associated protein kinase 2, Death-associated protein kinase 2, DRP 1, DRP-1, DRP1, MGC119312.

Background: Protein kinase termed (DAPK2) dependant on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase, a protein kinase involved in apoptosis. Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis. Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling.

Gene ID: 23604