GDI1 antibody (AA 1-100) (HRP)

Catalog No. ABIN1712533

Product Details anti-GDI1 Antibody (HRP)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Binding Specificity: AA 1-100

Reactivity: Mouse, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Chimpanzee, Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDI1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Alternative Name: GDI1 (GDI1 Products)

Synonyms: 1A antibody, GDIL antibody, MRX41 antibody, MRX48 antibody, OPHN2 antibody, RABGD1A antibody, RABGDIA antibody, XAP-4 antibody, GDIA antibody, GDIalpha antibody, GDI-1 antibody, zgc:110600 antibody, QccE-14779 antibody, Rab GDI alpha antibody, GDP dissociation inhibitor 1 antibody, GDP dissociation inhibitor 1 S homeolog antibody, guanosine diphosphate (GDP) dissociation inhibitor 1 antibody, GDI1 antibody, gdi1.S antibody, Gdi1 antibody, gdi1 antibody

Background:

Synonyms: 1A, FLJ41411, GDI-1, gdi1, GDIA_HUMAN, GDIL, GDP dissociation inhibitor 1, Guanosine diphosphate dissociation inhibitor 1, Mental retardation X-linked 41, Mental retardation X-linked 48, MRX41, MRX48, Oligophrenin 2, Oligophrenin-2, OPHN2, Protein XAP 4, Protein XAP-4, Protein XAP4, Rab GDI alpha, Rab GDP dissociation inhibitor alpha, RABGD1A, RABGDIA, XAP 4.

Background: Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).

Gene ID: 2664