Ggt5 Heavy Chain (Heavy Chain) antibody (PE)
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- Target
- Ggt5 Heavy Chain
- Binding Specificity
- Heavy Chain
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- PE
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Application
- Western Blotting (WB)
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 heavy chain
- Isotype
- IgG
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- Application Notes
- FCM(1:20-100)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Ggt5 Heavy Chain
- Synonyms
- GGT-REL antibody, GGTLA1 antibody, gamma-glutamyltransferase 5 antibody, GGT5 antibody
- Background
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Synonyms: Gamma glutamyl transpeptidase related enzyme, Gamma glutamyltranspeptidase 5, Gamma-glutamyl transpeptidase-related enzyme, Gamma-glutamyltransferase 5 heavy chain, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, GGT 5, GGT REL, GGT-rel, GGT5, GGT5_HUMAN, DKFZP566O011, GGTLA1, Glutathione hydrolase 5, Leukotriene-C4 hydrolase, Gamma-glutamyltransferase 5 heavy chain.
Background: g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4, it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.
- Gene ID
- 2687
- UniProt
- P36269
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