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ASPSCR1 antibody (AA 351-420)

ASPSCR1 Reactivity: Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1713923
  • Target See all ASPSCR1 Antibodies
    ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
    Binding Specificity
    • 14
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-420
    Reactivity
    • 53
    • 20
    • 14
    • 5
    • 4
    • 2
    • 1
    Mouse, Rat
    Host
    • 73
    • 7
    Rabbit
    Clonality
    • 73
    • 8
    Polyclonal
    Conjugate
    • 33
    • 8
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASPSCR1 antibody is un-conjugated
    Application
    • 62
    • 42
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TUG/ASPC
    Isotype
    IgG
    Top Product
    Discover our top product ASPSCR1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
    Alternative Name
    TUG/ASPC (ASPSCR1 Products)
    Synonyms
    tug antibody, aspl antibody, asps antibody, rcc17 antibody, ubxd9 antibody, aspcr1 antibody, ASPCR1 antibody, ASPL antibody, ASPS antibody, RCC17 antibody, TUG antibody, UBXD9 antibody, UBXN9 antibody, 1190006K01Rik antibody, ASPC antibody, ASPSCR1, UBX domain containing tether for SLC2A4 antibody, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antibody, alveolar soft part sarcoma chromosome region, candidate 1 antibody, alveolar soft part sarcoma chromosome region, candidate 1 (human) antibody, ASPSCR1 antibody, aspscr1.S antibody, Aspscr1 antibody, aspscr1 antibody, Bm1_55980 antibody
    Background

    Synonyms: Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma chromosome region candidate 1 human, Alveolar soft part sarcoma locus, ASPC, ASPC1_HUMAN, ASPCR 1, ASPCR1, ASPL, ASPS, ASPSCR 1, Aspscr1, FLJ45380, RCC 17, RCC17, renal cell carcinoma gene on chromosome 17, renal cell carcinoma papillary 17, Renal papillary cell carcinoma protein 17, Tether containing a UBX domain for GLUT4, Tether containing UBX domain for GLUT4, TUG, UBX domain containing protein 9, UBX domain protein 9, UBX domain-containing protein 9, UBXD 9, UBXD9, UBXN 9, UBXN9.

    Background: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.

    Gene ID
    79058
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