DNASEX antibody (AA 201-302)

Catalog No. ABIN1714436

Product Details anti-DNASEX Antibody

Target: DNASEX (Deoxyribonuclease X (DNASEX))

Binding Specificity: AA 201-302

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNASEX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNASE1L1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DNASEX

Target: DNASEX (Deoxyribonuclease X (DNASEX))

Alternative Name: DNASE1L1 (DNASEX Products)

Background:

Synonyms: Deoxyribonuclease I-like 1, Deoxyribonuclease I like 1, Deoxyribonuclease-1-like 1, DNAS1L1, DNase I like 1, DNase I like muscle specic, DNase I lysosomal like, DNase I-like 1, DNase X, DNASE1L1, DNASEX, DNL1L, DNSL1_HUMAN, Muscle specic DNase I like, DNASEX, Muscle-specic DNase I-like, XIB.

Background: DNASE1L1 is a 302 amino acid protein that localizes to the endoplasmic reticulum and belongs to the deoxyribonuclease family. Expressed at high levels in cardiac and skeletal muscle and at lower levels in a variety of tissues throughout the body, DNASE1L1 exists as multiple alternatively spliced isoforms and is thought to function in a similar manner to DNase l, possibly mediating internucleosomal DNA degradation via catalytic cleavage events. The gene encoding DNASE1L1 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Gene ID: 1774