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EPH Receptor A2 antibody

EPHA2 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 1B3C7 unconjugated
Catalog No. ABIN1724651
  • Target See all EPH Receptor A2 (EPHA2) Antibodies
    EPH Receptor A2 (EPHA2)
    Reactivity
    • 180
    • 129
    • 70
    • 14
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 191
    • 16
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 188
    • 24
    • 1
    Monoclonal
    Conjugate
    • 72
    • 20
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 10
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    This EPH Receptor A2 antibody is un-conjugated
    Application
    • 130
    • 79
    • 27
    • 27
    • 20
    • 14
    • 13
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of EphA2 expressed in E. coli.
    Clone
    1B3C7
    Isotype
    IgM
    Top Product
    Discover our top product EPHA2 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Abraham, Knapp, Cheng, Snyder, Mittal, Bangari, Kinch, Wu, Dhariwal, Mohammed: "Expression of EphA2 and Ephrin A-1 in carcinoma of the urinary bladder." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 2, pp. 353-60, (2006) (PubMed).

    Landen, Kinch, Sood: "EphA2 as a target for ovarian cancer therapy." in: Expert opinion on therapeutic targets, Vol. 9, Issue 6, pp. 1179-87, (2005) (PubMed).

  • Target
    EPH Receptor A2 (EPHA2)
    Alternative Name
    EphA2 (EPHA2 Products)
    Background

    Description: EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.

    Aliases: ECK, EPHA2

    Gene ID
    1969
    HGNC
    1969
    Pathways
    RTK Signaling
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