EPH Receptor A4 antibody (AA 777-986)

Catalog No. ABIN1724712

Product Details anti-EPH Receptor A4 Antibody

Target: EPH Receptor A4 (EPHA4)

Binding Specificity: AA 777-986

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of EphA4 (aa777-986) expressed in E. coli.

Clone: 7D3D4

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-EPH Receptor A4 antibody (ABIN1724712)

Takemoto, Fukuda, Sonoda, Murakami, Tanaka, Yamamoto: "Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro." in: The European journal of neuroscience, Vol. 16, Issue 6, pp. 1168-72, (2002) (PubMed).

Walkenhorst, Dütting, Handwerker, Huai, Tanaka, Drescher: "The EphA4 receptor tyrosine kinase is necessary for the guidance of nasal retinal ganglion cell axons in vitro." in: Molecular and cellular neurosciences, Vol. 16, Issue 4, pp. 365-75, (2001) (PubMed).

Wilkinson: "Multiple roles of EPH receptors and ephrins in neural development." in: Nature reviews. Neuroscience, Vol. 2, Issue 3, pp. 155-64, (2001) (PubMed).

Target Details for EPH Receptor A4

Target: EPH Receptor A4 (EPHA4)

Alternative Name: EphA4 (EPHA4 Products)

Synonyms: HEK8 antibody, SEK antibody, TYRO1 antibody, RGD1560587 antibody, ephe antibody, EPHA4 antibody, Ci-Eph1 antibody, sek antibody, hek8 antibody, rtk1 antibody, tyr01 antibody, 2900005C20Rik antibody, AI385584 antibody, Cek8 antibody, Hek8 antibody, Sek antibody, Sek1 antibody, Tyro1 antibody, rb antibody, XEpha4 antibody, sek-1 antibody, epha4 antibody, pag antibody, EphA4 antibody, apha3 antibody, ek2 antibody, epha3 antibody, sb:cb246 antibody, zek2 antibody, zgc:109882 antibody, EPH receptor A4 antibody, Eph receptor A4 antibody, ephrin receptor epsilon antibody, EPH receptor A4 S homeolog antibody, EPH receptor A4 L homeolog antibody, eph receptor A4a antibody, EPHA4 antibody, Epha4 antibody, ephe antibody, epha4 antibody, epha4.S antibody, epha4.L antibody, epha4a antibody

Background:

Description: EphA4: EPH receptor A4. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Aliases: SEK, HEK8, TYRO1

Gene ID: 2043

HGNC: 2043

Pathways: RTK Signaling