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CBX8 antibody (AA 17-222)

CBX8 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 9C3D4 unconjugated
Catalog No. ABIN1724765
  • Target See all CBX8 Antibodies
    CBX8 (Chromobox Homolog 8 (CBX8))
    Binding Specificity
    • 14
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-222
    Reactivity
    • 62
    • 44
    • 18
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 61
    • 8
    • 1
    Mouse
    Clonality
    • 63
    • 7
    Monoclonal
    Conjugate
    • 36
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX8 antibody is un-conjugated
    Application
    • 55
    • 31
    • 18
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. coli.
    Clone
    9C3D4
    Isotype
    IgG2b
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Dietrich, Bracken, Trinh, Schjerling, Koseki, Rappsilber, Helin, Hansen: "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).

  • Target
    CBX8 (Chromobox Homolog 8 (CBX8))
    Alternative Name
    CBX8 (CBX8 Products)
    Synonyms
    cbx8 antibody, MGC147589 antibody, Pc3 antibody, PC3 antibody, RC1 antibody, chromobox 8 antibody, chromobox 8 S homeolog antibody, chromobox homolog 8a (Pc class homolog, Drosophila) antibody, cbx8 antibody, CBX8 antibody, Cbx8 antibody, cbx8.S antibody, cbx8a antibody
    Background

    Description: Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus. , ,

    Aliases: PC3, RC1

    Molecular Weight
    43.4 kDa
    Gene ID
    57332
    HGNC
    57332
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