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GUCY1A1 antibody (AA 22-214)

GUCY1A1 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 3G6B2 unconjugated
Catalog No. ABIN1724787
  • Target See all GUCY1A1 Antibodies
    GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-214
    Reactivity
    • 36
    • 29
    • 14
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 6
    Mouse
    Clonality
    • 47
    • 4
    Monoclonal
    Conjugate
    • 25
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GUCY1A1 antibody is un-conjugated
    Application
    • 38
    • 19
    • 13
    • 13
    • 12
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. coli.
    Clone
    3G6B2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Cai, Hsieh, Gao, Kannan, Bhansali, Govardhan, Dutta, Shemshedini: "Soluble guanylyl cyclase ?1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 292-307, (2012) (PubMed).

    Zhong, Pan, Liu, Wang, Ying, Su, Huang, Tan: "A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 16, Issue 8, pp. 1227-39, (2011) (PubMed).

  • Target
    GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))
    Alternative Name
    GUCY1A3 (GUCY1A1 Products)
    Synonyms
    GC-SA3 antibody, GUC1A3 antibody, GUCA3 antibody, GUCSA3 antibody, GUCY1A1 antibody, 1200016O07Rik antibody, Gucy1a1 antibody, SGC antibody, im:7136149 antibody, sgc1a1 antibody, zgc:112159 antibody, gucy1a3 antibody, guanylate cyclase 1 soluble subunit alpha antibody, guanylate cyclase 1, soluble, alpha 3 antibody, guanylate cyclase 1 soluble subunit alpha 3 antibody, soluble guanylyl cyclase alpha subunit antibody, GUCY1A3 antibody, Gucy1a3 antibody, gucy1a3 antibody
    Background

    Description: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. , , ,

    Aliases: GUCA3, GC-SA3, GUC1A3, GUCSA3, GUCY1A1

    Molecular Weight
    77.5 kDa
    Gene ID
    2982
    HGNC
    2982
    Pathways
    Myometrial Relaxation and Contraction
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