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Integrin beta 4 antibody (AA 1619-1822)

ITGB4 Reactivity: Human WB, IHC, FACS, ELISA Host: Mouse Monoclonal 10B10D5 unconjugated
Catalog No. ABIN1724805
  • Target See all Integrin beta 4 (ITGB4) Antibodies
    Integrin beta 4 (ITGB4)
    Binding Specificity
    • 16
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1619-1822
    Reactivity
    • 80
    • 26
    • 25
    • 3
    • 3
    Human
    Host
    • 56
    • 35
    • 7
    • 2
    Mouse
    Clonality
    • 50
    • 50
    Monoclonal
    Conjugate
    • 52
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 4 antibody is un-conjugated
    Application
    • 50
    • 41
    • 30
    • 27
    • 19
    • 14
    • 14
    • 13
    • 13
    • 9
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.
    Clone
    10B10D5
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Liu, Qin, Liu, Xiang: "Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).

  • Target
    Integrin beta 4 (ITGB4)
    Alternative Name
    ITGB4 (ITGB4 Products)
    Synonyms
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    Background

    Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. , , ,

    Aliases: CD104

    Molecular Weight
    202 kDa
    Gene ID
    3691
    HGNC
    3691
    Pathways
    Integrin Complex
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