Decorin antibody (AA 263-324)

Catalog No. ABIN1724881

Product Details anti-Decorin Antibody

Target: Decorin (DCN)

Binding Specificity: AA 263-324

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Decorin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human DCN (AA: 263-324) expressed in E. coli.

Clone: 5E8E7

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-Decorin antibody (ABIN1724881)

Buraschi, Neill, Owens, Iniguez, Purkins, Vadigepalli, Evans, Schaefer, Peiper, Wang, Iozzo: "Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45559, (2012) (PubMed).

Adam, Saller, Ströbl, Hennebold, Dissen, Ojeda, Stouffer, Berg, Berg, Mayerhofer: "Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule." in: Human reproduction (Oxford, England), Vol. 27, Issue 11, pp. 3249-58, (2012) (PubMed).

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: DCN (DCN Products)

Synonyms: CSCD antibody, DSPG2 antibody, PG40 antibody, PGII antibody, PGS2 antibody, SLRR1B antibody, DC antibody, mDcn antibody, cscd antibody, dspg2 antibody, pg40 antibody, pgii antibody, pgs2 antibody, slrr1b antibody, decorin antibody, decorin L homeolog antibody, DCN antibody, Dcn antibody, dcn.L antibody, dcn antibody

Background:

Description: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. ,

Aliases: CSCD, PG40, PGII, PGS2, DSPG2, SLRR1B

Molecular Weight: 39.7 kDa

Gene ID: 1634

HGNC: 1634

Pathways: Glycosaminoglycan Metabolic Process