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GABBR2 antibody (AA 319-483)

GABBR2 Reactivity: Human WB, IHC, ELISA, ICC Host: Mouse Monoclonal 5G7F7 unconjugated
Catalog No. ABIN1724937
  • Target See all GABBR2 Antibodies
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Binding Specificity
    • 19
    • 15
    • 15
    • 15
    • 14
    • 13
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-483
    Reactivity
    • 89
    • 65
    • 59
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 105
    • 16
    Mouse
    Clonality
    • 97
    • 24
    Monoclonal
    Conjugate
    • 34
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABBR2 antibody is un-conjugated
    Application
    • 113
    • 52
    • 52
    • 37
    • 32
    • 16
    • 16
    • 14
    • 13
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. coli.
    Clone
    5G7F7
    Isotype
    IgG2a
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

  • Target
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Alternative Name
    GABBR2 (GABBR2 Products)
    Synonyms
    Gpr51 antibody, GABABR2 antibody, GPR51 antibody, GPRC3B antibody, HG20 antibody, HRIHFB2099 antibody, Gb2 antibody, Gm425 antibody, GABA(B)R2 antibody, si:dkey-190l1.2 antibody, gamma-aminobutyric acid type B receptor subunit 2 antibody, gamma-aminobutyric acid (GABA) B receptor, 2 antibody, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog antibody, GABBR2 antibody, LOC100448699 antibody, gabbr2 antibody, Gabbr2 antibody, gabbr2.S antibody
    Background

    Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. , , , ,

    Aliases: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099

    Molecular Weight
    105.8 kDa
    Gene ID
    9568
    HGNC
    9568
    Pathways
    cAMP Metabolic Process
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