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Neuroligin 3 antibody (AA 730-848) (Biotin)

NLGN3 Reactivity: Rat WB, IHC, ICC, IF Host: Mouse Monoclonal S110-29 Biotin
Catalog No. ABIN1741460
  • Target See all Neuroligin 3 (NLGN3) Antibodies
    Neuroligin 3 (NLGN3)
    Binding Specificity
    • 20
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 730-848
    Reactivity
    • 36
    • 33
    • 28
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 39
    • 27
    • 1
    • 1
    Mouse
    Clonality
    • 44
    • 24
    Monoclonal
    Conjugate
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuroligin 3 antibody is conjugated to Biotin
    Application
    • 40
    • 24
    • 22
    • 13
    • 13
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects ~110 kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.
    Clone
    S110-29
    Isotype
    IgG1
    Top Product
    Discover our top product NLGN3 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN1741460 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    Neuroligin 3 (NLGN3)
    Alternative Name
    Neuroligin 3 (NLGN3 Products)
    Synonyms
    Nlgn3 antibody, GB18290 antibody, hnl3 antibody, NLGN3 antibody, CCE-L1 antibody, NV16744 antibody, Nv1604741 antibody, HNL3 antibody, A230085M13Rik antibody, NL3 antibody, neuroligin 3 antibody, neuroligin 3 S homeolog antibody, NLG-3 antibody, nlgn3.S antibody, NLGN3 antibody, LOC659852 antibody, LOC100121155 antibody, nlgn3 antibody, Nlgn3 antibody
    Background
    Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
    Gene ID
    171297
    UniProt
    Q62889
    Pathways
    Synaptic Membrane
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