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SYNPO antibody (Isoform 2)

SYNPO Reactivity: Human, Mouse, Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1742348
  • Target See all SYNPO Antibodies
    SYNPO (Synaptopodin (SYNPO))
    Binding Specificity
    • 16
    • 9
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-452, Isoform 2
    Reactivity
    • 34
    • 28
    • 25
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 4
    • 3
    Rabbit
    Clonality
    • 50
    • 4
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYNPO antibody is un-conjugated
    Application
    • 42
    • 14
    • 13
    • 9
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Specificity
    Fragment used for immunization is present in all 3 isoforms.
    Purification
    antiserum
    Immunogen
    Recombinant mouse synaptopodin (aa 331-452 in isoform 2).
  • Application Notes
    WB: 1 : 1000 (AP staining)
    IP: not tested yet
    ICC: 1 : 600
    IHC: 1 : 250 up to 1 : 500
    IHC-P: 1 : 250 up to 1 : 500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS
    Handling Advice
    Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
    Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.
    Storage
    4 °C/-20 °C
    Storage Comment
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Sugar, Wassenhove-McCarthy, Orr, Green, van Kuppevelt, McCarthy: "N-sulfation of heparan sulfate is critical for syndecan-4-mediated podocyte cell-matrix interactions." in: American journal of physiology. Renal physiology, Vol. 310, Issue 10, pp. F1123-35, (2016) (PubMed).

    Fester, Zhou, Ossig, Labitzke, Bläute, Bader, Vollmer, Jarry, Rune: "Synaptopodin is regulated by aromatase activity." in: Journal of neurochemistry, Vol. 140, Issue 1, pp. 126-139, (2016) (PubMed).

    Collier, OMalley, Rademacher, Stancati, Sisson, Sortwell, Paumier, Gebremedhin, Steece-Collier: "Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration." in: Neurobiology of disease, Vol. 77, pp. 191-203, (2015) (PubMed).

    Dieni, Nestel, Sibbe, Frotscher, Hellwig: "Distinct synaptic and neurochemical changes to the granule cell-CA3 projection in Bassoon mutant mice." in: Frontiers in synaptic neuroscience, Vol. 7, pp. 18, (2015) (PubMed).

    Spada, Rojas, Pérez-Yagüe, Mulens, Cannata-Ortiz, Bragado, Barber: "NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery." in: Journal of leukocyte biology, Vol. 97, Issue 3, pp. 583-98, (2015) (PubMed).

    Sun, Qu, Zhang, Caruana, Bertram, Li: "Glomerular endothelial cell injury and damage precedes that of podocytes in adriamycin-induced nephropathy." in: PLoS ONE, Vol. 8, Issue 1, pp. e55027, (2013) (PubMed).

    Cohen, Louneva, Han, Hodes, Wilson, Bennett, Lucki, Arnold: "Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain." in: Synapse (New York, N.Y.), Vol. 65, Issue 8, pp. 763-70, (2011) (PubMed).

    Chen, Wassenhove-McCarthy, Yamaguchi, Holzman, van Kuppevelt, Orr, Funk, Woods, McCarthy: "Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices." in: Kidney international, Vol. 78, Issue 11, pp. 1088-99, (2010) (PubMed).

    Tarabra, Giunti, Barutta, Salvidio, Burt, Deferrari, Gambino, Vergola, Pinach, Perin, Camussi, Gruden: "Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes." in: Diabetes, Vol. 58, Issue 9, pp. 2109-18, (2009) (PubMed).

    Vlachos, Korkotian, Schonfeld, Copanaki, Deller, Segal: "Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 4, pp. 1017-33, (2009) (PubMed).

  • Target
    SYNPO (Synaptopodin (SYNPO))
    Alternative Name
    Synaptopodin (SYNPO Products)
    Synonyms
    SYNPO antibody, DKFZp459N012 antibody, 9030217H17Rik antibody, 9130229N11 antibody, 9330140I15Rik antibody, AW046661 antibody, synaptopodin antibody, formin-like protein 5 antibody, SYNPO antibody, LOC100147046 antibody, Synpo antibody
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