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P2RX7 antibody (C-Term)

P2RX7 Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1742370
  • Target See all P2RX7 Antibodies
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Binding Specificity
    • 15
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 363-595, C-Term
    Reactivity
    • 58
    • 40
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 57
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 58
    • 4
    Polyclonal
    Conjugate
    • 28
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RX7 antibody is un-conjugated
    Application
    • 48
    • 26
    • 23
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Specificity
    Specific for P2X7.
    Purification
    Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
    Immunogen
    Recombinant cytoplasmic C-terminal tail of mouse P2X7 (aa 363-595).
    Top Product
    Discover our top product P2RX7 Primary Antibody
  • Application Notes
    WB: 1 : 1000 (AP staining)
    IP: not tested yet
    ICC: not tested yet
    IHC: not tested yet
    Comment

    Detects mouse protein with higher sensitivity. This antibody detects an additional band at 30 kDa of unknown identity.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
    Buffer
    PBS
    Handling Advice
    Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.
    Storage
    -20 °C
    Storage Comment
    Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
  • Young, Sinadinos, Lefebvre, Chan, Arkle, Vaudry, Gorecki: "A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90." in: Autophagy, Vol. 11, Issue 1, pp. 113-30, (2015) (PubMed).

    Young, Brutkowski, Lien, Arkle, Lochmüller, Zabłocki, Górecki: "P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment." in: Journal of cellular and molecular medicine, Vol. 16, Issue 5, pp. 1026-37, (2012) (PubMed).

    Masin, Young, Lim, Barnes, Xu, Marschall, Brutkowski, Mooney, Gorecki, Murrell-Lagnado: "Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockouts." in: British journal of pharmacology, Vol. 165, Issue 4, pp. 978-93, (2012) (PubMed).

  • Target
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Alternative Name
    P2X7 (P2RX7 Products)
    Synonyms
    p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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