Lymphocyte Antigen 9 (LY9) antibody (Biotin)

Antigen: Lymphocyte Antigen 9 (LY9)

Synonyms: hly9, mLY9, CD229, SLAMF3, LY9, MGC139478, Ly-9, T100, Lgp100, AI893573

Clonality: Monoclonal (Ly9ab3)

Host: Hamster

Reactivity: Mouse (Murine)

Conjugate: Biotin

Application: Flow Cytometry (FACS)

Catalog no.: ABIN179778

Additional Information

Alternative name: CD229 (Ly-9)

Immunogen: AHK cells transiently transfected with mouse CD229 (Ly-9)

Isotype: IgG

Clone: Ly9ab3

Description: CD229 is a 100-120 kD glycoprotein. It is a member of the SLAM family, a CD2 subset of the Ig superfamily, known as Ly9 or SLAMF3. CD229 is expressed on T cells, B cells, NK cells, and thymocytes. It functions as a homophilic adhesion molecule through binding to CD229 itself. The cytoplasmic tail of CD229 binds to SAP and Grb2 proteins. CD229 is involved in enhancing T cell activation and Th2 polarization. Distribution: T cells, B cells, NK cells, thymocytes Function: Homophilic adhesion, T cell activation, Th2 cell polarization Synonyms: Ly9, SLAMF3 Structure: 100-120 kD glycoprotein, SLAM family, CD2 subset of Ig superfamily

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 10 cells in 100 µl. It is recommended that the reagent be titrated for optimal performance for each application.

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Storage: The antibody solution should be stored undiluted at 4°C. Do not freeze.

Research Area: CD Antigens

Restrictions: For Research Use only