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Mannose Receptor, C Type 1 (MRC1) antibody (FITC)
| Antigen | Mannose Receptor, C Type 1 (MRC1) |
| Synonyms | MMR, CD206, CLEC13D, MR, AW259686, mrc1, MGC86525, MRC1L1, MRC1 |
| Clonality | Monoclonal (MR5D3) |
| Host |
 Alternatives Rat |
| Reactivity |
Alternatives Mouse (Murine) |
| Conjugate |
Alternatives FITC |
| Application |
Alternatives Flow Cytometry (FACS)
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| Catalog no. | ABIN179827 |
| Quantity | 200 µg (Variants) |
| Price | Product not available in this region. |
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Additional Information
| Alternative name | CD206 (MMR) |
| Immunogen | Mannose Receptor CRD4-7-Fc fusion protein |
| Isotype | IgG2a, kappa chain |
| Clone | MR5D3 |
| Description | CD206, known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belongs to C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, langerhans cells and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis, as well as activation of macrophages and antigen presentation, and plays an important role in host defense and provides a link between innate and adaptive immunity Distribution: Macrophages, dendritic cells, Langerhans cells, liver endothelial cells Function: Pathogen recognition, endocytosis and phagocytosis, antigen presentation Synonyms: MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1 Structure: Type I transmembrane protein, 175 kD, C-type lectin superfamily |
Application Details
| Application Notes | Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting, and immunohistochemical staining of frozen sections. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 1.0 µg per 10 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Purification | The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Storage | The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Research Area | CD Antigens |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Mannose Receptor, C Type 1 (MRC1)", type "Antibodies"
| Hosts | Mouse (7), Rat (6) |
| Reactivities | Human (7), Mouse (Murine) (6) |
| Applications | Flow Cytometry (FACS) (8), Western Blotting (WB) (8), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Enzyme Immunoassay (EIA) (3), Immunoprecipitation (IP) (3), Immunofluorescence (IF) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2) |
| Conjugates | Biotin (1), FITC (1), PE (1) |
