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CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody (PE)
| Antigen | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) |
| Synonyms | p50, Bp50, CDW40, MGC9013, TNFRSF5, IGM, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, CD40 |
| Clonality | Monoclonal (G28-5) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Conjugate |
Alternatives PE |
| Application |
Alternatives Flow Cytometry (FACS)
|
| Catalog no. | ABIN179867 |
| Quantity | 100 tests (Variants) |
| Price | Product not available in this region. |
| Shipping to |
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Additional Information
| Alternative name | CD40 |
| Isotype | IgG1, kappa chain |
| Clone | G28-5 |
| Description | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The G28.5 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA. Distribution: B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts Function: B cell differentiation, costimulation, isotype class-switching, rescues B cells from apoptosis Synonyms: BP50, TNFRSF5 Structure: TNFR superfamily, type I glycoprotein, 48 kD |
Application Details
| Application Notes | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Additional reported applications (for the relevant formats) include: B cell bioassays. For immunofluorescent staining, the suggested use of this reagent is 20 µl per 1 million cells or 20 µl per 100 µl of whole blood. |
| Purification | The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). |
| Storage | The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Research Area | CD Antigens |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40)", type "Antibodies"
| Hosts | Mouse (111), Rat (60), Rabbit (20), Hamster (10) |
| Reactivities | Human (125), Mouse (Murine) (78), Rat (Rattus) (7), Chicken (4), Dog (Canine) (3), Monkey (3), Pig (Porcine) (2) |
| Applications | Flow Cytometry (FACS) (152), Immunoprecipitation (IP) (33), Western Blotting (WB) (30), Immunohistochemistry (Frozen Sections) (IHC (fro)) (29), ELISA (26), Functional Studies (Func) (18), Immunohistochemistry (IHC) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), Enzyme Immunoassay (EIA) (8), Immunofluorescence (IF) (6), Blocking Antibody (Inhibition) (2), Immunocytochemistry (ICC) (2), Blocking Antibody (Inhibition) (1), ELISA (Detection) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1) |
| Conjugates | FITC (29), Biotin (28), PE (23), APC (9), RPE (5), SPRD (3), Cy5,PE (2), Cy5.5,PE (2), Alexa Fluor 488 (1) |
| Epitopes | pThr254 (1) |
