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CD69 (CD69) antibody (Biotin)

Antigen

CD69 (CD69)

Synonyms CLEC2C
Clonality Monoclonal (FN50)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alternatives Biotin
Application
Alternatives Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
Catalog no. ABIN179879
Quantity 100 µg  (Variants)
Price Product not available in this region.
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Additional Information

Alternative name CD69
Isotype IgG1, kappa chain
Clone FN50
Description CD69 is a 27-33 kD type II transmembrane protein, also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells and certain CD4 T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells. Distribution: Activated T cells, B cells, NK cells, granulocytes, thymocytes, platelets, Langerhans cells Function: Lymphocyte, monocyte, and platelet activation, NK cell killing Synonyms: Very Early Activation Antigen (VEA), Activation inducer molecule (AIM) Structure: C-type lectin, type II glycoprotein, 28/32 kD

Application Details

Application Notes Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage The antibody solution should be stored undiluted at 4°C. Do not freeze.
Research Area CD Antigens
Restrictions For Research Use only

Alternatives

Alternatives for antigen "CD69 (CD69)", type "Antibodies"
Hosts Mouse (63), Hamster (52), Rabbit (4)
Reactivities Human (66), Mouse (Murine) (54), Rat (Rattus) (3)
Applications Flow Cytometry (FACS) (112), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Immunoprecipitation (IP) (17), Western Blotting (WB) (13), Functional Studies (Func) (6), ELISA (4), Immunofluorescence (IF) (4), Immunohistochemistry (IHC) (4), ELISA (Detection) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Enzyme Immunoassay (EIA) (2)
Conjugates FITC (19), PE (16), Biotin (11), APC (7), Cy7,PE (5), RPE (4), Cy5,PE (3), Cy5.5 (2), RPE,Cy5 (2), Alexa Fluor 700 (1), PE,Cy5 (1), PE,Cy7 (1), PerCP (1), SPRD (1)