CD10 antibody (APC/Cy7)

Antigen: CD10

Clonality: Monoclonal (HI10a)

Host: Mouse

Reactivity: Human

Conjugate: APC,Cy7

Application: Flow Cytometry (FACS)

Catalog no.: ABIN179880

Additional Information

Isotype: IgG1, kappa chain

Clone: HI10a

Description: CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein, also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides. Distribution: B cell precursors, T cell precursors, neutrophils Function: Zinc-binding metalloproteinase, B cell development Synonyms: Common acute lymphoblastic leukemia antigen (CALLA), Enkephalinase, Neutral endopeptidase, Neprilysin Structure: Type II transmembrane metalloprotease family, 100 kD

Application Details

Application Notes: Additional reported (for the relevant formats) applications include: Western blotting. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 µl per million cells or 20 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Purification: The antibody was purified by affinity chromatography, and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Research Area: Surface Receptors of Immune Cells, CD Antigens

Restrictions: For Research Use only