CD56 (NCAM) antibody (Biotin)
| Antigen |
|
| Clonality |
Monoclonal (HCD56) |
|
Host
|
|
|
Reactivity
|
|
|
Conjugate
|
|
|
Application
|
|
| Catalog no. |
ABIN179897 |
| Quantity |
100 µg (Variants) |
| Price |
Product not available in this region.
|
| Shipping to |
|
|
Isotype
|
IgG1, kappa chain
|
|
Clone
|
HCD56
|
|
Description
|
CD56 is a single transmembrane glycoprotein also known as N-CAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate. Distribution: NK cells, T subset, neural tissue, some LGL and myeloid leukemias Function: Adhesion Synonyms: NCAM, Leu-19, NKH1 Structure: Ig superfamily, single transmembrane or GPI-anchored glycoprotein, 175-185 kD
|
|
Application Notes
|
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 10 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
|
|
Purification
|
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin and unconjugated antibody.
|
|
Buffer
|
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
|
|
Storage
|
The antibody solution should be stored undiluted at 4°C. Do not freeze.
|
|
Research Area
|
CD Antigens
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "CD56 (NCAM)", type "Antibodies"
|
Hosts
|
Mouse (9)
|
|
Reactivities
|
Human (8), Cow (Bovine) (1)
|
|
Applications
|
Flow Cytometry (FACS) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1)
|
|
Conjugates
|
Biotin (3), FITC (1), PE (1), PE,Cy5.5 (1), SPRD (1)
|
Alternatives 
