OX40 Ligand antibody

Antigen: OX40 Ligand

Synonyms: LOC100008595

Clonality: Monoclonal (11C3-1)

Host: Mouse

Reactivity: Human

Application: Flow Cytometry (FACS)

Catalog no.: ABIN179968

Additional Information

Alternative name: OX40 Ligand (CD252| OX40L)

Format: Purified

Isotype: IgG1, kappa chain

Clone: 11C3-1

Description: OX40 ligand (OX40L) is a 35 kD type II transmembrane protein which belongs to TNF superfamily, also known as gp34, CD252, CD134L or TNFSF4. The OX40 ligand is expressed on activated B cells, activated endothelial cells, mature dendritic cells, activated CTLs, activated mast cells, and airway smooth muscle cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to regulate T cell proliferation and differentiation, and to enhance immunoglobulin secretion by activated B cells. Distribution: Activated B cells, activated endothelial cells, mature dendritic cells, airway smooth muscle cells Function: B-cell/T-cell interaction, costimulation Synonyms: Gp34, OX40L, CD134L, CD252, TNFSF4 Structure: NGF/TNF superfamily, 35 kD

Application Details

Application Notes: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 10 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Purification: The antibody was purified by affinity chromatography.

Buffer: Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 µm filter sterilized. Endotoxin level is < 0.1 EU/µg of the protein (< 0.01 ng/µg of the protein) as determined by the LAL test.

Storage: The antibody solution should be stored undiluted at 4 °C. This LEAF(TM) solution contains no preservative, handle under aseptic conditions.

Restrictions: For Research Use only