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ILT7 (CD85g) antibody

Antigen

ILT7 (CD85g)
Clonality Monoclonal (17G10-2)
Host

Mouse
Reactivity

Human
Application
Flow Cytometry (FACS)
Catalog no. ABIN179978
Quantity 500 µg  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Secondary Antibodies Variants back to top

Format Purified
Isotype IgG1, kappa chain  (Matching secondary antibodies)
Clone 17G10-2
Description ILT7 (immunoglobulin-like transcript 7) is a member of leukocyte immunoglobulin-like receptor (LIR or LILR) gene family, also known as CD85g and LILRA4. It contains four extracellular Ig domains. In association with FcepsilonR1gamma, ILT7 forms a receptor complex that transduces ITAM-mediated signals. ILT7 is specifically expressed on plasmacytoid dendritic cells (pDCs), but not on myeloid dendritic cells and other peripheral blood leukocytes. ILT7 negatively regulates the innate immune functions of human pDCs. Cross-linking 17G10.2 antibody is able to trigger ILT7 mediated signaling. Distribution: Plasmacytoid dendritic cells Function: Negatively regulates pDC mediated innate immune function Synonyms: CD85g, immunoglobulin-like transcript 7, LILRA4 Structure: Associate with FcepsilonR1gamma leukocyte immunoglobulin-like receptor gene family

Application Details
Secondary Antibodies Variants back to top

Application Notes Additional reported (for the relevant formats) applications include: trigger ILT7 mediated signaling.The LEAF(TM) purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm sterile-filtered) is recommended for functional assays (ABIN179978). Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 0.5 µg per 10 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Purification The antibody was purified by affinity chromatography.
Buffer Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 µm filter sterilized. Endotoxin level is < 0.1 EU/µg of the protein (< 0.01 ng/µg of the protein) as determined by the LAL test.
Storage The antibody solution should be stored undiluted at 4 °C. This LEAF(TM) solution contains no preservative, handle under aseptic conditions.
Restrictions For Research Use only