Microtubule Associated Protein 2 A/b (MAP2a/b) antibody

Antigen: Microtubule Associated Protein 2 A/b (MAP2a/b)

Clonality: Monoclonal (MT-08)

Host: Mouse

Reactivity: Human, Pig (Porcine), Mouse (Murine)

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), ELISA

Catalog no.: ABIN180018

Additional Information

Alternative name: Microtubule Associated Protein 2ab (MAP2ab)

Immunogen: Microtubule protein enriched for kinesin

Format: Purified

Isotype: IgG1, kappa chain  (Matching secondary antibodies)

Clone: MT-08

Description: Microtubule associated protein 2 also know as MAP2, has three isoforms that include two high molecular weight forms MAP2A and MAP2B (~280KD), and a low molecular weight form MAB2C (~70KD). MAP2 belongs to the microtubule-associated protein family and expressed in the nervous system. The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. MAP2 has been shown to interact with Fyn, Grb2, PRKACA, and CPEB1. The MT-08 antibody has been shown to be useful for Western blotting, Immunoprecipitation, Immunohistochemistry (frozen sections), Immunocytochemistry, and ELISA of the human, mouse and porcine MAP2A and MAP2B isoforms. Distribution: Cytoplasm protein, expressed in the nervous system. Function: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Synonyms: Microtubule associated protein 2, MAP2 Structure: MAP2 belongs to the microtubule-associated protein family. MAP2 has three isoforms that include two high molecular weight forms MAP2A and MAP2B (~280KD), and a low molecular weight form MAB2C (~70KD).

Specificity: Fyn, Grb2, PRKACA, and CPEB1.

Application Details

Application Notes: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 µg antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.

Purification: The antibody was purified by protein G affinity chromatography.

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.

Storage: Upon receipt, store undiluted at 4° C.

Restrictions: For Research Use only

Images

anti-Microtubule Associated Protein 2 A/b (MAP2a/b) antibody